Evaluation of Disulfide Bond Position to Enhance the Thermal Stability of a Highly Stable Single Domain Antibody

Open Access

Peer-reviewed

Research Article

Dan Zabetakis,

Affiliation Center for Bio/Molecular Science and Engineering, US Naval Research Laboratory, Washington, DC, United States of America
⨯
Mark A. Olson,

Affiliation Department of Cell Biology and Biochemistry, USAMRIID, Frederick, Maryland 21702, United States of America
⨯
George P. Anderson,

Affiliation Center for Bio/Molecular Science and Engineering, US Naval Research Laboratory, Washington, DC, United States of America
⨯
Patricia M. Legler,

Affiliation Center for Bio/Molecular Science and Engineering, US Naval Research Laboratory, Washington, DC, United States of America
⨯
Ellen R. Goldman

* E-mail: ellen.goldman@nrl.navy.mil

Affiliation Center for Bio/Molecular Science and Engineering, US Naval Research Laboratory, Washington, DC, United States of America
⨯

Reader Comments (0)

Disulfide bonds
Is the Subject Area "Disulfide bonds" applicable to this article?

Thanks for your feedback.
Melting
Is the Subject Area "Melting" applicable to this article?

Thanks for your feedback.
Melting point
Is the Subject Area "Melting point" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Fluorescent dyes
Is the Subject Area "Fluorescent dyes" applicable to this article?

Thanks for your feedback.
Cysteine
Is the Subject Area "Cysteine" applicable to this article?

Thanks for your feedback.
Biochemical simulations
Is the Subject Area "Biochemical simulations" applicable to this article?

Thanks for your feedback.
Denaturation
Is the Subject Area "Denaturation" applicable to this article?

Thanks for your feedback.