Intestinal NADPH Oxidase 2 Activity Increases in a Neonatal Rat Model of Necrotizing Enterocolitis

Scott R. Welak; Rebecca M. Rentea; Ru-Jeng Teng; Nathan Heinzerling; Ben Biesterveld; Jennifer L. Liedel; Kirkwood A. Pritchard Jr; Katherine M. Fredrich; David M. Gourlay

doi:10.1371/journal.pone.0115317

Loading metrics

Open Access

Peer-reviewed

Research Article

Intestinal NADPH Oxidase 2 Activity Increases in a Neonatal Rat Model of Necrotizing Enterocolitis

Scott R. Welak ,

* E-mail: swelak@mcw.edu

Affiliations Division of Neonatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Translational Vascular Biology Program, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Rebecca M. Rentea,

Affiliations Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Ru-Jeng Teng,

Affiliations Division of Neonatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Translational Vascular Biology Program, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Nathan Heinzerling,

Affiliations Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Ben Biesterveld,

Affiliations Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Jennifer L. Liedel,

Affiliations Division of Neonatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Critical Care, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Kirkwood A. Pritchard Jr,

Affiliations Translational Vascular Biology Program, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Katherine M. Fredrich,

Affiliations Translational Vascular Biology Program, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
David M. Gourlay

Affiliations Children's Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Translational Vascular Biology Program, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America, Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯

Intestinal NADPH Oxidase 2 Activity Increases in a Neonatal Rat Model of Necrotizing Enterocolitis

Scott R. Welak,
Rebecca M. Rentea,
Ru-Jeng Teng,
Nathan Heinzerling,
Ben Biesterveld,
Jennifer L. Liedel,
Kirkwood A. Pritchard Jr,
Katherine M. Fredrich,
David M. Gourlay

Published: December 17, 2014
https://doi.org/10.1371/journal.pone.0115317

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gastrointestinal tract
Is the Subject Area "Gastrointestinal tract" applicable to this article?

Thanks for your feedback.
Reverse transcriptase-polymerase chain reaction
Is the Subject Area "Reverse transcriptase-polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Superoxides
Is the Subject Area "Superoxides" applicable to this article?

Thanks for your feedback.
Hypoxia
Is the Subject Area "Hypoxia" applicable to this article?

Thanks for your feedback.
Immunofluorescence
Is the Subject Area "Immunofluorescence" applicable to this article?

Thanks for your feedback.
Nitric oxide
Is the Subject Area "Nitric oxide" applicable to this article?

Thanks for your feedback.
Oxidative stress
Is the Subject Area "Oxidative stress" applicable to this article?

Thanks for your feedback.
Pathogenesis
Is the Subject Area "Pathogenesis" applicable to this article?

Thanks for your feedback.