18F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma

Mette Kjoelhede Nedergaard; Signe Regner Michaelsen; Thomas Urup; Helle Broholm; Henrik El Ali; Hans Skovgaard Poulsen; Marie-Thérése Stockhausen; Andreas Kjaer; Ulrik Lassen

doi:10.1371/journal.pone.0115315

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Open Access

Peer-reviewed

Research Article

¹⁸F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma

Mette Kjoelhede Nedergaard ,

* E-mail: Mette.Kjoelhede.Nedergaard@regionh.dk

Affiliation Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark
⨯
Signe Regner Michaelsen,

Affiliation Department of Radiation Biology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark
⨯
Thomas Urup,

Affiliation Department of Radiation Biology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark
⨯
Helle Broholm,

Affiliation Department of Neuropathology, Center of Diagnostic Investigation, Rigshospitalet, Copenhagen, Denmark
⨯
Henrik El Ali,

Affiliation Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark
⨯
Hans Skovgaard Poulsen,

Affiliation Department of Radiation Biology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark
⨯
Marie-Thérése Stockhausen,

Affiliation Department of Radiation Biology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark
⨯
Andreas Kjaer ,

Contributed equally to this work with: Andreas Kjaer, Ulrik Lassen

Affiliation Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark
⨯
Ulrik Lassen

Contributed equally to this work with: Andreas Kjaer, Ulrik Lassen

Affiliation Phase 1 Unit, Department of Oncology, The Finsen Center, Rigshospitalet, Copenhagen, Denmark
⨯

¹⁸F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma

Mette Kjoelhede Nedergaard,
Signe Regner Michaelsen,
Thomas Urup,
Helle Broholm,
Henrik El Ali,
Hans Skovgaard Poulsen,
Marie-Thérése Stockhausen,
Andreas Kjaer,
Ulrik Lassen

Published: February 13, 2015
https://doi.org/10.1371/journal.pone.0115315

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