HCV 3a Core Protein Increases Lipid Droplet Cholesteryl Ester Content via a Mechanism Dependent on Sphingolipid Biosynthesis

• Ursula Loizides-Mangold ,

  Contributed equally to this work with: Ursula Loizides-Mangold, Sophie Clément

  Affiliation Department of Biochemistry, NCCR Chemical Biology, University of Geneva, Geneva, Switzerland

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• Sophie Clément ,

  Contributed equally to this work with: Ursula Loizides-Mangold, Sophie Clément

  Affiliation Division of Clinical Pathology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland

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• Alba Alfonso-Garcia,

  Affiliation University of California Irvine, Beckman Laser Institute, Irvine, California, United States of America

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• Emilie Branche,

  Affiliation Division of Clinical Pathology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland

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• Stéphanie Conzelmann,

  Affiliation Division of Clinical Pathology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland

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• Clotilde Parisot,

  Affiliation Division of Clinical Pathology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland

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• Eric O. Potma,

  Affiliation University of California Irvine, Beckman Laser Institute, Irvine, California, United States of America

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• Howard Riezman ,

  ¶These authors also contributed equally to this work.

  Affiliation Department of Biochemistry, NCCR Chemical Biology, University of Geneva, Geneva, Switzerland

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• Francesco Negro

  * E-mail: francesco.negro@hcuge.ch

  Affiliations Division of Clinical Pathology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland, Divisions of Gastroenterology and Hepatology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland

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