Abieslactone Induces Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinomas through the Mitochondrial Pathway and the Generation of Reactive Oxygen Species

Open Access

Peer-reviewed

Research Article

Guo-Wei Wang ,

Contributed equally to this work with: Guo-Wei Wang, Chao Lv

Affiliation School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, PR China
⨯
Chao Lv ,

Contributed equally to this work with: Guo-Wei Wang, Chao Lv

Affiliations School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China, School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fujian 350108, PR China
⨯
Zhi-Ran Shi,

Affiliation School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
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Ren-Tao Zeng,

Affiliation School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
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Xue-Yun Dong,

Affiliation School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fujian 350108, PR China
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Wei-Dong Zhang,

Affiliations School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, PR China, School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
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Run-Hui Liu,

Affiliation School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
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Lei Shan ,

* E-mail: shenyunheng@hotmail.com (YHS); shanleicn@126.com (LS)

Affiliation School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
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Yun-Heng Shen

* E-mail: shenyunheng@hotmail.com (YHS); shanleicn@126.com (LS)

Affiliation School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China
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Apoptosis
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Mitochondria
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Cell cycle and cell division
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Cancer treatment
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G1 phase
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Flow cytometry
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Hepatocellular carcinoma
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Cyclins
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