An HIV-1 Envelope Immunogen with W427S Mutation in CD4 Binding Site Induced More T Follicular Helper Memory Cells and Reduced Non-Specific Antibody Responses

• Hao-Tong Yu,

  Affiliation Department of Microbiology, Harbin Medical University, Harbin, China

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• Dan Tian,

  Affiliation Department of Microbiology, Harbin Medical University, Harbin, China

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• Jia-Ye Wang,

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Cai-Xia Guo,

  Affiliation Department of Microbiology, Harbin Medical University, Harbin, China

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• Yan Li,

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Xin Wang,

  Affiliation Department of Microbiology, Harbin Medical University, Harbin, China

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• Di Li,

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Feng-Min Zhang,

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Min Zhuang ,

  * E-mail: zhuangm@ems.hrbmu.edu.cn (MZ); lingh@ems.hrbmu.edu.cn (HL)

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Hong Ling

  * E-mail: zhuangm@ems.hrbmu.edu.cn (MZ); lingh@ems.hrbmu.edu.cn (HL)

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Lab for Infection and Immunity, Key Lab of Etiology of Heilongjiang Province Education Bureau, Harbin, China, Department of Parasitology, Harbin Medical University, Harbin, China

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