Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans

Shingo Matsuyama; Masataka Moriuchi; Mary Ann Suico; Shuichiro Yano; Saori Morino-Koga; Tsuyoshi Shuto; Kunitoshi Yamanaka; Tatsuya Kondo; Eiichi Araki; Hirofumi Kai

doi:10.1371/journal.pone.0114690

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Peer-reviewed

Research Article

Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans

Shingo Matsuyama,

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Masataka Moriuchi,

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Mary Ann Suico,

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Shuichiro Yano,

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Saori Morino-Koga,

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Tsuyoshi Shuto,

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Kunitoshi Yamanaka,

Affiliation Department of Molecular Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto City, Japan
⨯
Tatsuya Kondo,

Affiliation Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Eiichi Araki,

Affiliation Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto City, Japan
⨯
Hirofumi Kai

* E-mail: hirokai@gpo.kumamoto-u.ac.jp

Affiliation Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto City, Japan
⨯

Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans

Shingo Matsuyama,
Masataka Moriuchi,
Mary Ann Suico,
Shuichiro Yano,
Saori Morino-Koga,
Tsuyoshi Shuto,
Kunitoshi Yamanaka,
Tatsuya Kondo,
Eiichi Araki,
Hirofumi Kai

Published: December 9, 2014
https://doi.org/10.1371/journal.pone.0114690

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