Functional Characterization of Nuclear Localization and Export Signals in Hepatitis C Virus Proteins and Their Role in the Membranous Web

Aviad Levin; Christopher J. Neufeldt; Daniel Pang; Kristen Wilson; Darci Loewen-Dobler; Michael A. Joyce; Richard W. Wozniak; D.  Lorne J Tyrrell

doi:10.1371/journal.pone.0114629

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Peer-reviewed

Research Article

Functional Characterization of Nuclear Localization and Export Signals in Hepatitis C Virus Proteins and Their Role in the Membranous Web

Aviad Levin ,

* E-mail: aviad@ualberta.ca (AL); rwozniak@ualberta.ca (RWW); lorne.tyrrell@ualberta.ca (DLJT)

Affiliations Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada, Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
⨯
Christopher J. Neufeldt,

Affiliation Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
⨯
Daniel Pang,

Affiliation Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
⨯
Kristen Wilson,

Affiliation Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
⨯
Darci Loewen-Dobler,

Affiliation Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
⨯
Michael A. Joyce,

Affiliation Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
⨯
Richard W. Wozniak ,

* E-mail: aviad@ualberta.ca (AL); rwozniak@ualberta.ca (RWW); lorne.tyrrell@ualberta.ca (DLJT)

Affiliation Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada
⨯
D. Lorne J Tyrrell

* E-mail: aviad@ualberta.ca (AL); rwozniak@ualberta.ca (RWW); lorne.tyrrell@ualberta.ca (DLJT)

Affiliation Li Ka Shing Institute of Virology, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada
⨯

Functional Characterization of Nuclear Localization and Export Signals in Hepatitis C Virus Proteins and Their Role in the Membranous Web

Aviad Levin,
Christopher J. Neufeldt,
Daniel Pang,
Kristen Wilson,
Darci Loewen-Dobler,
Michael A. Joyce,
Richard W. Wozniak,
D. Lorne J Tyrrell

Published: December 8, 2014
https://doi.org/10.1371/journal.pone.0114629

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Protein interactions
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Viral replication
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Signal peptides
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HIV-1
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Hepatitis C virus
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