Evaluation of a Density-Based Rapid Diagnostic Test for Sickle Cell Disease in a Clinical Setting in Zambia

Ashok A. Kumar; Catherine Chunda-Liyoka; Jonathan W. Hennek; Hamakwa Mantina; S. Y. Ryan Lee; Matthew R. Patton; Pauline Sambo; Silvester Sinyangwe; Chipepo Kankasa; Chifumbe Chintu; Carlo Brugnara; Thomas P. Stossel; George M. Whitesides

doi:10.1371/journal.pone.0114540

Loading metrics

Open Access

Peer-reviewed

Research Article

Evaluation of a Density-Based Rapid Diagnostic Test for Sickle Cell Disease in a Clinical Setting in Zambia

Ashok A. Kumar ,

Contributed equally to this work with: Ashok A. Kumar, Catherine Chunda-Liyoka

Affiliation School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Catherine Chunda-Liyoka ,

Contributed equally to this work with: Ashok A. Kumar, Catherine Chunda-Liyoka

Affiliation Department of Pediatrics, University Teaching Hospital, Lusaka, Zambia
⨯
Jonathan W. Hennek,

Affiliation Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Hamakwa Mantina,

Affiliation Department of Pediatrics, University Teaching Hospital, Lusaka, Zambia
⨯
S. Y. Ryan Lee,

Affiliation Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Matthew R. Patton,

Affiliation Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America
⨯
Pauline Sambo,

Affiliation Department of Pediatrics, University Teaching Hospital, Lusaka, Zambia
⨯
Silvester Sinyangwe,

Affiliation Department of Pediatrics, University Teaching Hospital, Lusaka, Zambia
⨯
Chipepo Kankasa,

Affiliation Department of Pediatrics, University Teaching Hospital, Lusaka, Zambia
⨯
Chifumbe Chintu,

Affiliation Department of Pediatrics, University Teaching Hospital, Lusaka, Zambia
⨯
Carlo Brugnara,

Affiliation Department of Laboratory Medicine, Children's Hospital Boston, Boston, Massachusetts, United States of America
⨯
Thomas P. Stossel,

Affiliation Hematology Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
⨯
George M. Whitesides

* E-mail: gwhitesides@gmwgroup.harvard.edu

Affiliations Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America, Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, United States of America
⨯

Evaluation of a Density-Based Rapid Diagnostic Test for Sickle Cell Disease in a Clinical Setting in Zambia

Ashok A. Kumar,
Catherine Chunda-Liyoka,
Jonathan W. Hennek,
Hamakwa Mantina,
S. Y. Ryan Lee,
Matthew R. Patton,
Pauline Sambo,
Silvester Sinyangwe,
Chipepo Kankasa,
Chifumbe Chintu

Published: December 9, 2014
https://doi.org/10.1371/journal.pone.0114540

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Red blood cells
Is the Subject Area "Red blood cells" applicable to this article?

Thanks for your feedback.
Blood
Is the Subject Area "Blood" applicable to this article?

Thanks for your feedback.
Hemoglobin
Is the Subject Area "Hemoglobin" applicable to this article?

Thanks for your feedback.
Sickle cell disease
Is the Subject Area "Sickle cell disease" applicable to this article?

Thanks for your feedback.
Zambia
Is the Subject Area "Zambia" applicable to this article?

Thanks for your feedback.
Diagnostic medicine
Is the Subject Area "Diagnostic medicine" applicable to this article?

Thanks for your feedback.
Centrifugation
Is the Subject Area "Centrifugation" applicable to this article?

Thanks for your feedback.
Capillaries
Is the Subject Area "Capillaries" applicable to this article?

Thanks for your feedback.