Suppression of the PI3K Pathway In Vivo Reduces Cystitis-Induced Bladder Hypertrophy and Restores Bladder Capacity Examined by Magnetic Resonance Imaging

Zhongwei Qiao; Chunmei Xia; Shanwei Shen; Frank D. Corwin; Miao Liu; Ruijuan Guan; John R. Grider; Li-Ya Qiao

doi:10.1371/journal.pone.0114536

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Peer-reviewed

Research Article

Suppression of the PI3K Pathway In Vivo Reduces Cystitis-Induced Bladder Hypertrophy and Restores Bladder Capacity Examined by Magnetic Resonance Imaging

Zhongwei Qiao ,

Contributed equally to this work with: Zhongwei Qiao, Chunmei Xia

Affiliation Children's Hospital of Fudan University, Division of Radiology, Shanghai, China
⨯
Chunmei Xia ,

Contributed equally to this work with: Zhongwei Qiao, Chunmei Xia

Affiliations Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, Shanghai, China, Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯
Shanwei Shen,

Affiliation Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯
Frank D. Corwin,

Affiliation Department of Radiology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯
Miao Liu,

Affiliation Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯
Ruijuan Guan,

Affiliation Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, Shanghai, China
⨯
John R. Grider,

Affiliations Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯
Li-Ya Qiao

* E-mail: lqiao2@vcu.edu

Affiliations Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
⨯

Suppression of the PI3K Pathway In Vivo Reduces Cystitis-Induced Bladder Hypertrophy and Restores Bladder Capacity Examined by Magnetic Resonance Imaging

Zhongwei Qiao,
Chunmei Xia,
Shanwei Shen,
Frank D. Corwin,
Miao Liu,
Ruijuan Guan,
John R. Grider,
Li-Ya Qiao

Published: December 8, 2014
https://doi.org/10.1371/journal.pone.0114536

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