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Open Access
Peer-reviewed
Research Article
Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation
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Marco Cardone,
Current address: Division of Therapeutic Proteins, Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Amiran K. Dzutsev,
Affiliations Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
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Hongchuan Li,
Affiliations Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
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Nicolas Riteau,
Affiliation Immunobiology Section, Laboratory of Parasitic Diseases, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Franca Gerosa,
Affiliation Department of Pathology, University of Verona, Verona, Italy
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Kevin Shenderov,
Affiliation Immunobiology Section, Laboratory of Parasitic Diseases, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Robin Winkler-Pickett,
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Lisa Provezza,
Affiliation Department of Pathology, University of Verona, Verona, Italy
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Elena Riboldi,
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Robert M. Leighty,
Affiliation Data Management Services, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
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Selinda J. Orr,
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Folkert Steinhagen,
Current address: Department for Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Mark D. Wewers,
Affiliation The Ohio State University, Davis Heart and Lung Research Institute, Columbus, Ohio, United States of America
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Alan Sher,
Affiliation Immunobiology Section, Laboratory of Parasitic Diseases, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Stephen K. Anderson,
Affiliations Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
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Romina Goldszmid,
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Daniel W. McVicar,
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Lyudmila Lyakh ,
Contributed equally to this work with: Lyudmila Lyakh, Giorgio Trinchieri
Affiliation Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
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Giorgio Trinchieri
Contributed equally to this work with: Lyudmila Lyakh, Giorgio Trinchieri
* E-mail: trinchig@mail.nih.gov
Affiliations Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America, The Trans-NIH Center for Human Immunology, Bethesda, Maryland, United States of America
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Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation
- Marco Cardone,
- Amiran K. Dzutsev,
- Hongchuan Li,
- Nicolas Riteau,
- Franca Gerosa,
- Kevin Shenderov,
- Robin Winkler-Pickett,
- Lisa Provezza,
- Elena Riboldi,
- Robert M. Leighty
- Published: December 4, 2014
- https://doi.org/10.1371/journal.pone.0114516