Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Claudia P. González-Hunt; Maxwell C. K. Leung; Rakesh K. Bodhicharla; Madeline G. McKeever; Andrew E. Arrant; Kathleen M. Margillo; Ian T. Ryde; Derek D. Cyr; Sara G. Kosmaczewski; Marc Hammarlund; Joel N. Meyer

doi:10.1371/journal.pone.0114459

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Open Access

Peer-reviewed

Research Article

Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Claudia P. González-Hunt ,

Contributed equally to this work with: Claudia P. González-Hunt, Maxwell C. K. Leung

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Maxwell C. K. Leung ,

Contributed equally to this work with: Claudia P. González-Hunt, Maxwell C. K. Leung

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Rakesh K. Bodhicharla,

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Madeline G. McKeever,

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Andrew E. Arrant,

Affiliation Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina, United States of America
⨯
Kathleen M. Margillo,

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Ian T. Ryde,

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Derek D. Cyr,

Affiliation Center for Applied Genomics and Technology, Duke University, Durham, North Carolina, United States of America
⨯
Sara G. Kosmaczewski,

Affiliation Department of Genetics, Program in Cellular Neuroscience, Neurodegeneration, and Repair, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Marc Hammarlund,

Affiliation Department of Genetics, Program in Cellular Neuroscience, Neurodegeneration, and Repair, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Joel N. Meyer

* E-mail: mailto:joel.meyer@duke.edu

Affiliation Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯

Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Claudia P. González-Hunt,
Maxwell C. K. Leung,
Rakesh K. Bodhicharla,
Madeline G. McKeever,
Andrew E. Arrant,
Kathleen M. Margillo,
Ian T. Ryde,
Derek D. Cyr,
Sara G. Kosmaczewski,
Marc Hammarlund

Published: December 8, 2014
https://doi.org/10.1371/journal.pone.0114459

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Mitochondrial DNA
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Dopaminergics
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DNA damage
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Caenorhabditis elegans
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