MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer

Jiaojiao Su; Hongwei Liang; Weiyan Yao; Nan Wang; Suyang Zhang; Xin Yan; Hui Feng; Wenjing Pang; Yanbo Wang; Xueliang Wang; Zhen Fu; Yanqing Liu; Chihao Zhao; Junfeng Zhang; Chen-Yu Zhang; Ke Zen; Xi Chen; Yalei Wang

doi:10.1371/journal.pone.0114420

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Peer-reviewed

Research Article

MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer

Jiaojiao Su ,

Contributed equally to this work with: Jiaojiao Su, Hongwei Liang, Weiyan Yao

Affiliation Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China
⨯
Hongwei Liang ,

Contributed equally to this work with: Jiaojiao Su, Hongwei Liang, Weiyan Yao

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Weiyan Yao ,

Contributed equally to this work with: Jiaojiao Su, Hongwei Liang, Weiyan Yao

Affiliation Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
⨯
Nan Wang,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Suyang Zhang,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Xin Yan,

Affiliation The Comprehensive Cancer Center of Drum Tower Hospital affiliated to Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu 210008, China
⨯
Hui Feng,

Affiliation Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China
⨯
Wenjing Pang,

Affiliation Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
⨯
Yanbo Wang,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Xueliang Wang,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Zhen Fu,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Yanqing Liu,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Chihao Zhao,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Junfeng Zhang,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Chen-Yu Zhang,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Ke Zen,

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
Xi Chen ,

* E-mail: xichen@nju.edu.cn (XC); alei416@163.com (YW)

Affiliation Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China
⨯
[ ... ],
Yalei Wang

* E-mail: xichen@nju.edu.cn (XC); alei416@163.com (YW)

Affiliation Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China
⨯
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MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer

Jiaojiao Su,
Hongwei Liang,
Weiyan Yao,
Nan Wang,
Suyang Zhang,
Xin Yan,
Hui Feng,
Wenjing Pang,
Yanbo Wang,
Xueliang Wang

Published: December 4, 2014
https://doi.org/10.1371/journal.pone.0114420

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