Tacrolimus (FK506) Suppresses TREM-1 Expression at an Early but Not at a Late Stage in a Murine Model of Fungal Keratitis

Weilan Huang; Shiqi Ling; Xiuhua Jia; Binwu Lin; Xi Huang; Jing Zhong; Weihua Li; Xiaolei Lin; Yifang Sun; Jin Yuan

doi:10.1371/journal.pone.0114386

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Open Access

Peer-reviewed

Research Article

Tacrolimus (FK506) Suppresses TREM-1 Expression at an Early but Not at a Late Stage in a Murine Model of Fungal Keratitis

Weilan Huang ,

Contributed equally to this work with: Weilan Huang, Shiqi Ling

Affiliations State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China, Physical Examination Center, The Third Affiliated Hospital of Sun Yat-Sen University-Lingnan Hospital, Guangzhou, China
⨯
Shiqi Ling ,

Contributed equally to this work with: Weilan Huang, Shiqi Ling

Affiliation Department of Ophthalmology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
⨯
Xiuhua Jia,

Affiliation Department of Ophthalmology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
⨯
Binwu Lin,

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯
Xi Huang,

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯
Jing Zhong,

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯
Weihua Li,

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯
Xiaolei Lin,

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯
Yifang Sun,

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯
Jin Yuan

* E-mail: yuanjincornea@126.com

Affiliation State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center of Sun Yat-sen University, Guangzhou, China
⨯

Tacrolimus (FK506) Suppresses TREM-1 Expression at an Early but Not at a Late Stage in a Murine Model of Fungal Keratitis

Weilan Huang,
Shiqi Ling,
Xiuhua Jia,
Binwu Lin,
Xi Huang,
Jing Zhong,
Weihua Li,
Xiaolei Lin,
Yifang Sun,
Jin Yuan

Published: December 2, 2014
https://doi.org/10.1371/journal.pone.0114386

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