Lenalidomide Induces Lipid Raft Assembly to Enhance Erythropoietin Receptor Signaling in Myelodysplastic Syndrome Progenitors

Kathy L. McGraw; Ashley A. Basiorka; Joseph O. Johnson; Justine Clark; Gisela Caceres; Eric Padron; Ruth Heaton; Yukiyasu Ozawa; Sheng Wei; Lubomir Sokol; Alan F. List

doi:10.1371/journal.pone.0114249

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Open Access

Peer-reviewed

Research Article

Lenalidomide Induces Lipid Raft Assembly to Enhance Erythropoietin Receptor Signaling in Myelodysplastic Syndrome Progenitors

Kathy L. McGraw,

Affiliation Department of Malignant Hematology, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, United States of America
⨯
Ashley A. Basiorka,

Affiliation Department of Malignant Hematology, H. Lee Moffitt Cancer Center-Cancer Biology Ph.D. Program, University of South Florida, 12902 Magnolia Drive, Tampa, FL, 33612, United States of America
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Joseph O. Johnson,

Affiliation Analytic Microscopy Core Facility, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, United States of America
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Justine Clark,

Affiliation Department of Malignant Hematology, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, United States of America
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Gisela Caceres,

Affiliation Morsani Molecular Diagnostic Laboratory, H. Lee Moffitt Cancer Center, 10902 N. McKinley Drive, Tampa, FL, 33612, United States of America
⨯
Eric Padron,

Affiliation Department of Malignant Hematology, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, United States of America
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Ruth Heaton,

Affiliation Department of Pathology, University of Arizona, 1501 N Campbell Ave, Tucson, AZ, 85724, United States of America
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Yukiyasu Ozawa,

Affiliation Department of Hematology, Japanese Red Cross Nagoya First Hospital, 3-35 Michishita-cho, Nakamura-ku, Aichi, 453-8511, Japan
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Sheng Wei,

Affiliation Department of Immunology, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive Tampa, FL, 33612, United States of America
⨯
Lubomir Sokol,

Affiliation Department of Malignant Hematology, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, United States of America
⨯
Alan F. List

* E-mail: Alan.List@moffitt.org

Affiliation Department of Malignant Hematology, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, United States of America
⨯

Lenalidomide Induces Lipid Raft Assembly to Enhance Erythropoietin Receptor Signaling in Myelodysplastic Syndrome Progenitors

Kathy L. McGraw,
Ashley A. Basiorka,
Joseph O. Johnson,
Justine Clark,
Gisela Caceres,
Eric Padron,
Ruth Heaton,
Yukiyasu Ozawa,
Sheng Wei,
Lubomir Sokol

Published: December 3, 2014
https://doi.org/10.1371/journal.pone.0114249

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STAT signaling
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