β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

Bruce X. Wong; Andrew Tsatsanis; Linh Q. Lim; Paul A. Adlard; Ashley I. Bush; James A. Duce

doi:10.1371/journal.pone.0114174

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Research Article

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

Bruce X. Wong,

Affiliation Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia
⨯
Andrew Tsatsanis,

Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom
⨯
Linh Q. Lim,

Affiliations Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia, Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Victoria, Australia
⨯
Paul A. Adlard,

Affiliations Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia
⨯
Ashley I. Bush ,

* E-mail: ashley.bush@florey.edu.au (AIB); J.A.Duce@leeds.ac.uk (JAD)

Affiliations Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia
⨯
James A. Duce

* E-mail: ashley.bush@florey.edu.au (AIB); J.A.Duce@leeds.ac.uk (JAD)

Affiliations Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom, Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia
⨯

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

Bruce X. Wong,
Andrew Tsatsanis,
Linh Q. Lim,
Paul A. Adlard,
Ashley I. Bush,
James A. Duce

Published: December 2, 2014
https://doi.org/10.1371/journal.pone.0114174

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