A Quantitative MRI Method for Imaging Blood-Brain Barrier Leakage in Experimental Traumatic Brain Injury

Wei Li; Justin Alexander Long; Lora Talley Watts; Zhao Jiang; Qiang Shen; Yunxia Li; Timothy Q. Duong

doi:10.1371/journal.pone.0114173

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Open Access

Peer-reviewed

Research Article

A Quantitative MRI Method for Imaging Blood-Brain Barrier Leakage in Experimental Traumatic Brain Injury

Wei Li ,

Contributed equally to this work with: Wei Li, Justin Alexander Long

* E-mail: liw5@uthscsa.edu (WL); duongt@uthscsa.edu (TQD)

Affiliations Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Justin Alexander Long ,

Contributed equally to this work with: Wei Li, Justin Alexander Long

Affiliation Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Lora Talley Watts,

Affiliations Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Cellular and Structure Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Zhao Jiang,

Affiliation Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Qiang Shen,

Affiliation Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Yunxia Li,

Affiliation Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Timothy Q. Duong

* E-mail: liw5@uthscsa.edu (WL); duongt@uthscsa.edu (TQD)

Affiliations Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, South Texas Veterans Health Care System, Department of Veterans Affairs, San Antonio, Texas, United States of America
⨯

A Quantitative MRI Method for Imaging Blood-Brain Barrier Leakage in Experimental Traumatic Brain Injury

Wei Li,
Justin Alexander Long,
Lora Talley Watts,
Zhao Jiang,
Qiang Shen,
Yunxia Li,
Timothy Q. Duong

Published: December 5, 2014
https://doi.org/10.1371/journal.pone.0114173

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Traumatic brain injury
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Blood-brain barrier
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Blood-brain barrier permeability assay
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Brain damage
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