Crushed and Injected Buprenorphine Tablets: Characteristics of Princeps and Generic Solutions

Régis Bouquié; Laura Wainstein; Paul Pilet; Jean-Marie Mussini; Guillaume Deslandes; Johann Clouet; Eric Dailly; Pascale Jolliet; Caroline Victorri-Vigneau

doi:10.1371/journal.pone.0113991

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Open Access

Peer-reviewed

Research Article

Crushed and Injected Buprenorphine Tablets: Characteristics of Princeps and Generic Solutions

Régis Bouquié ,

* E-mail: regis.bouquie@chu-nantes.fr

Affiliations Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France, EA 4275 Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France
⨯
Laura Wainstein,

Affiliation Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France
⨯
Paul Pilet,

Affiliations INSERM (Institut National de la Santé et de la Recherche Médicale), UMR (Unité Mixte de Recherche) 791, Laboratoire d’Ingénierie Ostéo-Articulaire et Dentaire (LIOAD), Université de Nantes, Nantes, France, Centre Hospitalier Universitaire de Nantes, Pôle Hospitalo-Universitaire 4, Nantes, France
⨯
Jean-Marie Mussini,

Affiliation Laboratoire d'Anatomie Pathologique, Centre Hospitalier Universitaire de Nantes, Nantes, France
⨯
Guillaume Deslandes,

Affiliation Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France
⨯
Johann Clouet,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche en Santé (UMRS) 791, Laboratoire d’Ingénierie Ostéo-Articulaire et Dentaire (LIOAD), Université de Nantes, Nantes, France, Centre Hospitalier Universitaire Nantes, Pôle Hospitalo-Universitaire (PHU) 7, Pharmacie Centrale, Nantes, France
⨯
Eric Dailly,

Affiliations Clinical Pharmacology, Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France, EA 3826 Thérapeutiques Cliniques et Expérimentales des Infections, Université de Nantes, Nantes, France
⨯
Pascale Jolliet,

Affiliations EA 4275 Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France, Clinical Pharmacology, Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France
⨯
Caroline Victorri-Vigneau

Affiliations EA 4275 Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France, Pharmacology, Service de Pharmacologie Clinique, Centre Hospitalier Universitaire de Nantes, Nantes, France
⨯

Crushed and Injected Buprenorphine Tablets: Characteristics of Princeps and Generic Solutions

Régis Bouquié,
Laura Wainstein,
Paul Pilet,
Jean-Marie Mussini,
Guillaume Deslandes,
Johann Clouet,
Eric Dailly,
Pascale Jolliet,
Caroline Victorri-Vigneau

Published: December 4, 2014
https://doi.org/10.1371/journal.pone.0113991

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