Recombinant Factor VIIa Reduces Bleeding after Blunt Liver Injury in a Pig Model of Dilutional Coagulopathy under Severe Hypothermia

• Henri M. H. Spronk,

  Affiliation Laboratory for Clinical Thrombosis and Haemostasis, Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands

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• Till Braunschweig,

  Affiliation Department of Pathology, RWTH Aachen University Hospital, Aachen, Germany

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• Rolf Rossaint,

  Affiliation Department of Anaesthesiology, RWTH Aachen University Hospital, Aachen, Germany

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• Dirk C. Wüst,

  Affiliation Department of Anaesthesiology, RWTH Aachen University Hospital, Aachen, Germany

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• Rene van Oerle,

  Affiliation Laboratory for Clinical Thrombosis and Haemostasis, Department of Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands

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• Brian Lauritzen,

  Affiliation Novo Nordisk A/S, Novo Nordisk Park G2P.S, Måløv, Denmark

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• Rene Tolba,

  Affiliation Institute for Laboratory Animal Science, RWTH Aachen University Hospital, Aachen, Germany

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• Oliver Grottke

  * E-mail: ogrottke@ukaachen.de

  Affiliation Department of Anaesthesiology, RWTH Aachen University Hospital, Aachen, Germany

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