Intradermal Administration of the Type II Heat-Labile Enterotoxins LT-IIb and LT-IIc of Enterotoxigenic Escherichia coli Enhances Humoral and CD8⁺ T Cell Immunity to a Co-Administered Antigen

• John C. Hu,

  Affiliation Department of Microbiology & Immunology and The Witebsky Center for Microbial Pathogenesis and Immunology, The University at Buffalo, Buffalo, New York, United States of America

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• Camila Mathias-Santos,

  Affiliation Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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• Christopher J. Greene,

  Affiliation Department of Microbiology & Immunology and The Witebsky Center for Microbial Pathogenesis and Immunology, The University at Buffalo, Buffalo, New York, United States of America

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• Natalie D. King-Lyons,

  Affiliation Department of Microbiology & Immunology and The Witebsky Center for Microbial Pathogenesis and Immunology, The University at Buffalo, Buffalo, New York, United States of America

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• Juliana F. Rodrigues,

  Affiliation Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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• George Hajishengallis,

  Affiliation University of Pennsylvania School of Dental Medicine, Department of Microbiology, Philadelphia, Pennsylvania, United States of America

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• Luís C. S. Ferreira ,

  ¶These authors are co-senior authors on this work.

  Affiliation Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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• Terry D. Connell

  * E-mail: connell@buffalo.edu

  ¶These authors are co-senior authors on this work.

  Affiliation Department of Microbiology & Immunology and The Witebsky Center for Microbial Pathogenesis and Immunology, The University at Buffalo, Buffalo, New York, United States of America

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