The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

Kristin T. Chun; Binghui Li; Erika Dobrota; Courtney Tate; Jeong-Heon Lee; Shehnaz Khan; Laura Haneline; Harm HogenEsch; David G. Skalnik

doi:10.1371/journal.pone.0113745

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Research Article

The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

Kristin T. Chun ,

Contributed equally to this work with: Kristin T. Chun, Binghui Li

Affiliations Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Biology Department, Indiana University-Purdue University Indianapolis School of Science, Indianapolis, Indiana, United States of America
⨯
Binghui Li ,

Contributed equally to this work with: Kristin T. Chun, Binghui Li

Affiliation Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Erika Dobrota,

Affiliation Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Courtney Tate,

Affiliations Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Jeong-Heon Lee,

Affiliation Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Shehnaz Khan,

Affiliation Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Laura Haneline,

Affiliations Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Departments of Microbiology & Immunology and Cellular & Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Harm HogenEsch,

Affiliation Department of Comparative Pathobiology, Purdue University, West Lafayette, Indiana, United States of America
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David G. Skalnik

* E-mail: dskalnik@iupui.edu

Affiliations Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Biology Department, Indiana University-Purdue University Indianapolis School of Science, Indianapolis, Indiana, United States of America
⨯

The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

Kristin T. Chun,
Binghui Li,
Erika Dobrota,
Courtney Tate,
Jeong-Heon Lee,
Shehnaz Khan,
Laura Haneline,
Harm HogenEsch,
David G. Skalnik

Published: December 3, 2014
https://doi.org/10.1371/journal.pone.0113745

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Bone marrow cells
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DNA methylation
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Apoptosis
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Cell differentiation
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Cytosine
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