Experimental Myocardial Infarction Induces Altered Regulatory T Cell Hemostasis, and Adoptive Transfer Attenuates Subsequent Remodeling

Rinat Sharir; Jonathan Semo; Sara Shimoni; Tamar Ben-Mordechai; Natalie Landa-Rouben; Sofia Maysel-Auslender; Aviv Shaish; Michal Entin–Meer; Gad Keren; Jacob George

doi:10.1371/journal.pone.0113653

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Peer-reviewed

Research Article

Experimental Myocardial Infarction Induces Altered Regulatory T Cell Hemostasis, and Adoptive Transfer Attenuates Subsequent Remodeling

Rinat Sharir,

Affiliations Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel, Laboratory of Cardiovascular Research, Department of Cardiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Jonathan Semo,

Affiliations Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel, Laboratory of Cardiovascular Research, Department of Cardiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel
⨯
Sara Shimoni,

Affiliations Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Tamar Ben-Mordechai,

Affiliation Neufeld Cardiac Research Institute, Tel Aviv University, Sheba Center for Regenerative Medicine, Stem Cells, and Tissue Engineering and Tamman Cardiovascular Research institute, Ramat-Gan, Israel
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Natalie Landa-Rouben,

Affiliation Neufeld Cardiac Research Institute, Tel Aviv University, Sheba Center for Regenerative Medicine, Stem Cells, and Tissue Engineering and Tamman Cardiovascular Research institute, Ramat-Gan, Israel
⨯
Sofia Maysel-Auslender,

Affiliations Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Aviv Shaish,

Affiliation The Bert W. Strassburger Lipid Center, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel
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Michal Entin–Meer,

Affiliations Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Gad Keren,

Affiliations Laboratory of Cardiovascular Research, Department of Cardiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Jacob George

* E-mail: jgeorge@bezeqint.net

Affiliation Heart Center, Kaplan Medical Center, Rehovot, Israel, Affiliated to the Hebrew University, Jerusalem, Israel
⨯

Experimental Myocardial Infarction Induces Altered Regulatory T Cell Hemostasis, and Adoptive Transfer Attenuates Subsequent Remodeling

Rinat Sharir,
Jonathan Semo,
Sara Shimoni,
Tamar Ben-Mordechai,
Natalie Landa-Rouben,
Sofia Maysel-Auslender,
Aviv Shaish,
Michal Entin–Meer,
Gad Keren,
Jacob George

Published: December 1, 2014
https://doi.org/10.1371/journal.pone.0113653

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Regulatory T cells
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Myocardial infarction
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Heart
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Echocardiography
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Adoptive transfer
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Intravenous injections
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Cardiac ventricles
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T cells
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