A Single Chain Variant of Factor VIII Fc Fusion Protein Retains Normal In Vivo Efficacy but Exhibits Altered In Vitro Activity

• Yang Buyue,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Tongyao Liu,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• John D. Kulman,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Garabet G. Toby,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• George D. Kamphaus,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Susannah Patarroyo-White,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Qi Lu,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Thomas J. Reidy,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Baisong Mei,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Haiyan Jiang,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Glenn F. Pierce,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Jurg M. Sommer,

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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• Robert T. Peters

  * E-mail: robert.peters@biogenidec.com

  Affiliation Hematology Research, Biogen Idec, Cambridge, Massachusetts, United States of America

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