Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target

• Sudagar S. Gurcha ,

  Contributed equally to this work with: Sudagar S. Gurcha, Veeraraghavan Usha

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Veeraraghavan Usha ,

  Contributed equally to this work with: Sudagar S. Gurcha, Veeraraghavan Usha

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Jonathan A. G. Cox,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Klaus Fütterer,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Katherine A. Abrahams,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Apoorva Bhatt,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Luke J. Alderwick,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Robert C. Reynolds,

  Affiliation Department of Chemistry, University of Alabama at Birmingham, College of Arts and Sciences, 1530 3rd Avenue South, Birmingham, Alabama, 35294-1240, United States of America

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• Nicholas J. Loman,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• VijayaShankar Nataraj,

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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• Carlos Alemparte,

  Affiliation Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain

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• David Barros,

  Affiliation Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain

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• Adrian J. Lloyd,

  Affiliation Department of Life Sciences, University of Warwick, Coventry, CV4 7AL, United Kingdom

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• Lluis Ballell,

  Affiliation Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, 28760, Tres Cantos, Madrid, Spain

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• Judith V. Hobrath,

  Affiliation Organic Chemistry Department, Southern Research Institute, Birmingham, Alabama, 35205, United States of America

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•  [ ... ],
• Gurdyal S. Besra

  * E-mail: g.besra@bham.ac.uk

  Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

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