Oligonucleotide Arrays vs. Metaphase-Comparative Genomic Hybridisation and BAC Arrays for Single-Cell Analysis: First Applications to Preimplantation Genetic Diagnosis for Robertsonian Translocation Carriers

Laia Ramos; Javier del Rey; Gemma Daina; Manel García-Aragonés; Lluís Armengol; Alba Fernandez-Encinas; Mònica Parriego; Montserrat Boada; Olga Martinez-Passarell; Maria Rosa Martorell; Oriol Casagran; Jordi Benet; Joaquima Navarro

doi:10.1371/journal.pone.0113223

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Peer-reviewed

Research Article

Oligonucleotide Arrays vs. Metaphase-Comparative Genomic Hybridisation and BAC Arrays for Single-Cell Analysis: First Applications to Preimplantation Genetic Diagnosis for Robertsonian Translocation Carriers

Laia Ramos,

Affiliation Unitat de Biologia Cel·lular i Genètica Mèdica, Facultat de Medicina, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain
⨯
Javier del Rey,

Affiliation Unitat de Biologia Cel·lular i Genètica Mèdica, Facultat de Medicina, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain
⨯
Gemma Daina,

Affiliation Unitat de Biologia Cel·lular i Genètica Mèdica, Facultat de Medicina, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain
⨯
Manel García-Aragonés,

Affiliation Qgenomics Laboratory, 08003, Barcelona, Spain
⨯
Lluís Armengol,

Affiliation Qgenomics Laboratory, 08003, Barcelona, Spain
⨯
Alba Fernandez-Encinas,

Affiliation Unitat de Biologia Cel·lular i Genètica Mèdica, Facultat de Medicina, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain
⨯
Mònica Parriego,

Affiliation Institut Universitari Dexeus, 08028, Barcelona, Spain
⨯
Montserrat Boada,

Affiliation Institut Universitari Dexeus, 08028, Barcelona, Spain
⨯
Olga Martinez-Passarell,

Affiliation Fundació Puigvert, Hospital de Sant Pau i de la Santa Creu, 08025, Barcelona, Spain
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Maria Rosa Martorell,

Affiliation Unitat de Reproducció Humana i Diagnòstic Genètic, Clínica Girona, 17002, Girona, Spain
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Oriol Casagran,

Affiliation Genomic Service, Center for Research in Agricultural Genomics (CRAG), 08193, Bellaterra, Spain
⨯
Jordi Benet,

Affiliation Unitat de Biologia Cel·lular i Genètica Mèdica, Facultat de Medicina, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain
⨯
Joaquima Navarro

* E-mail: Joaquima.Navarro@uab.cat

Affiliation Unitat de Biologia Cel·lular i Genètica Mèdica, Facultat de Medicina, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain
⨯

Oligonucleotide Arrays vs. Metaphase-Comparative Genomic Hybridisation and BAC Arrays for Single-Cell Analysis: First Applications to Preimplantation Genetic Diagnosis for Robertsonian Translocation Carriers

Laia Ramos,
Javier del Rey,
Gemma Daina,
Manel García-Aragonés,
Lluís Armengol,
Alba Fernandez-Encinas,
Mònica Parriego,
Montserrat Boada,
Olga Martinez-Passarell,
Maria Rosa Martorell

Published: November 21, 2014
https://doi.org/10.1371/journal.pone.0113223

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Oligonucleotides
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Blastomeres
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Aneuploidy
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Fibroblasts
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Chromosomal translocations
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