MDM4 Overexpressed in Acute Myeloid Leukemia Patients with Complex Karyotype and Wild-Type TP53

Li Li; Yanhong Tan; Xiuhua Chen; Zhifang Xu; Siyao Yang; Fanggang Ren; Haixiu Guo; Xiaojuan Wang; Yi Chen; Guoxia Li; Hongwei Wang

doi:10.1371/journal.pone.0113088

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Open Access

Peer-reviewed

Research Article

MDM4 Overexpressed in Acute Myeloid Leukemia Patients with Complex Karyotype and Wild-Type TP53

Li Li,

Affiliations Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China, Department of biology, School of Basic Medicine, Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Yanhong Tan,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Xiuhua Chen,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Zhifang Xu,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Siyao Yang,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Fanggang Ren,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Haixiu Guo,

Affiliation Department of biology, School of Basic Medicine, Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Xiaojuan Wang,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Yi Chen,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Guoxia Li,

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯
Hongwei Wang

* E-mail: wanghw68@hotmail.com

Affiliation Department of Hematology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, P.R. China
⨯

MDM4 Overexpressed in Acute Myeloid Leukemia Patients with Complex Karyotype and Wild-Type TP53

Li Li,
Yanhong Tan,
Xiuhua Chen,
Zhifang Xu,
Siyao Yang,
Fanggang Ren,
Haixiu Guo,
Xiaojuan Wang,
Yi Chen,
Guoxia Li

Published: November 18, 2014
https://doi.org/10.1371/journal.pone.0113088

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Karyotypes
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Acute myeloid leukemia
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Cell proliferation
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Polyploidy
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Cell cycle and cell division
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Gene expression
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