Changing Folding and Binding Stability in a Viral Coat Protein: A Comparison between Substitutions Accessible through Mutation and Those Fixed by Natural Selection

• Craig R. Miller ,

  Contributed equally to this work with: Craig R. Miller, Kuo Hao Lee

  Affiliations Department of Biological Sciences, University of Idaho, Moscow, Idaho, Department of Mathematics, University of Idaho, Moscow, Idaho, Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho

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• Kuo Hao Lee ,

  Contributed equally to this work with: Craig R. Miller, Kuo Hao Lee

  Affiliations Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho, Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas

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• Holly A. Wichman,

  Affiliations Department of Biological Sciences, University of Idaho, Moscow, Idaho, Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho

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• F. Marty Ytreberg

  * E-mail: ytreberg@uidaho.edu

  Affiliations Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, Idaho, Department of Physics, University of Idaho, Moscow, Idaho

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