Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial

• Else M. Bijker ,

  Contributed equally to this work with: Else M. Bijker, Remko Schats

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Remko Schats ,

  Contributed equally to this work with: Else M. Bijker, Remko Schats

  Affiliation Leiden University Medical Center, Department of Infectious Diseases, PO Box 9600, 2300 RC Leiden, The Netherlands

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• Joshua M. Obiero,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Marije C. Behet,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Geert-Jan van Gemert,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Marga van de Vegte-Bolmer,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Wouter Graumans,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Lisette van Lieshout,

  Affiliations Leiden University Medical Center, Department of Medical Microbiology, PO Box 9600, 2300 RC Leiden, The Netherlands, Leiden University Medical Center, Department of Parasitology, PO Box 9600, 2300 RC Leiden, The Netherlands

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• Guido J. H. Bastiaens,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Karina Teelen,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Cornelus C. Hermsen,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Anja Scholzen,

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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• Leo G. Visser,

  Affiliation Leiden University Medical Center, Department of Infectious Diseases, PO Box 9600, 2300 RC Leiden, The Netherlands

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• Robert W. Sauerwein

  * E-mail: Robert.Sauerwein@radboudumc.nl

  Affiliation Radboud university medical center, Department of Medical Microbiology, PO Box 9101, 6500 HB Nijmegen, The Netherlands

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