Deletion of Apoptosis Signal-Regulating Kinase 1 (ASK1) Protects Pancreatic Beta-Cells from Stress-Induced Death but Not from Glucose Homeostasis Alterations under Pro-Inflammatory Conditions

• Emilie Pepin,

  Affiliation Betagenex Inc, Laval, QC, Canada, H7V5B7

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• Arisa Higa,

  Affiliation Inserm U1053, Team Endoplasmic Reticulum Stress and Cancer, Université de Bordeaux, Bordeaux, France, 33076

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• Carole Schuster-Klein,

  Affiliation Groupe de Recherche Servier, Suresnes, France, 92284 Cedex

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• Catherine Bernard,

  Affiliation Groupe de Recherche Servier, Suresnes, France, 92284 Cedex

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• Thierry Sulpice,

  Affiliations Betagenex Inc, Laval, QC, Canada, H7V5B7, Physiogenex SAS, Labège, France, 31670

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• Beatrice Guardiola,

  Affiliation Groupe de Recherche Servier, Suresnes, France, 92284 Cedex

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• Eric Chevet,

  Affiliation Inserm U1053, Team Endoplasmic Reticulum Stress and Cancer, Université de Bordeaux, Bordeaux, France, 33076

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• Thierry Alquier

  * E-mail: thierry.alquier@umontreal.ca

  Affiliation Montreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM), and Departments of Medicine, Biochemistry and Cell Biology and Pathology, Université de Montréal, Montréal, QC, Canada, H3T 1J4

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