Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

Keiyu Oshida; Naresh Vasani; Russell S. Thomas; Dawn Applegate; Mitch Rosen; Barbara Abbott; Christopher Lau; Grace Guo; Lauren M. Aleksunes; Curtis Klaassen; J. Christopher Corton

doi:10.1371/journal.pone.0112655

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Open Access

Peer-reviewed

Research Article

Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

Keiyu Oshida,

Current address: Toray Industries, Inc., Kanagawa, Japan

Affiliation National Health and Environmental Effects Research Lab, US-EPA, Research Triangle Park, North Carolina, United States of America
⨯
Naresh Vasani,

Affiliation National Health and Environmental Effects Research Lab, US-EPA, Research Triangle Park, North Carolina, United States of America
⨯
Russell S. Thomas,

Current address: National Center for Computational Toxicology, US-EPA, Research Triangle Park, North Carolina, United States of America

Affiliation Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, United States of America
⨯
Dawn Applegate,

Affiliation RegeneMed, San Diego, California, United States of America
⨯
Mitch Rosen,

Affiliation National Health and Environmental Effects Research Lab, US-EPA, Research Triangle Park, North Carolina, United States of America
⨯
Barbara Abbott,

Affiliation National Health and Environmental Effects Research Lab, US-EPA, Research Triangle Park, North Carolina, United States of America
⨯
Christopher Lau,

Affiliation National Health and Environmental Effects Research Lab, US-EPA, Research Triangle Park, North Carolina, United States of America
⨯
Grace Guo,

Affiliation Rutgers University, Ernest Mario School of Pharmacy, Department of Pharmacology and Toxicology, Piscataway, New Jersey, United States of America
⨯
Lauren M. Aleksunes,

Affiliation Rutgers University, Ernest Mario School of Pharmacy, Department of Pharmacology and Toxicology, Piscataway, New Jersey, United States of America
⨯
Curtis Klaassen,

Affiliation University of Washington, Seattle, Washington, United States of America
⨯
J. Christopher Corton

* E-mail: corton.chris@epa.gov

Affiliation National Health and Environmental Effects Research Lab, US-EPA, Research Triangle Park, North Carolina, United States of America
⨯

Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium

Keiyu Oshida,
Naresh Vasani,
Russell S. Thomas,
Dawn Applegate,
Mitch Rosen,
Barbara Abbott,
Christopher Lau,
Grace Guo,
Lauren M. Aleksunes,
Curtis Klaassen

Published: February 17, 2015
https://doi.org/10.1371/journal.pone.0112655

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