Unsupervised Deconvolution of Dynamic Imaging Reveals Intratumor Vascular Heterogeneity and Repopulation Dynamics

• Li Chen,

  Affiliations Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States of America, Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, United States of America

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• Peter L. Choyke,

  Affiliation Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States of America

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• Niya Wang,

  Affiliation Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, United States of America

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• Robert Clarke,

  Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D. C. 20057, United States of America

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• Zaver M. Bhujwalla,

  Affiliation Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States of America

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• Elizabeth M. C. Hillman,

  Affiliation Department of Biomedical Engineering, Columbia University, New York, NY 10027, United States of America

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• Ge Wang,

  Affiliation Department of Biomedical Engineering, Biomedical Imaging Center, Rensselaer Polytechnic Institute, Troy, NY 12180, United States of America

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• Yue Wang

  * E-mail: yuewang@vt.edu

  Affiliation Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, United States of America

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