A Physiologically-Motivated Compartment-Based Model of the Effect of Inhaled Hypertonic Saline on Mucociliary Clearance and Liquid Transport in Cystic Fibrosis

• Matthew R. Markovetz,

  Affiliation Department of Chemical and Petroleum Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, United States of America

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• Timothy E. Corcoran,

  Affiliations Department of Chemical and Petroleum Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, United States of America, Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America, Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, United States of America

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• Landon W. Locke,

  Affiliation Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

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• Michael M. Myerburg,

  Affiliation Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

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• Joseph M. Pilewski,

  Affiliation Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

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• Robert S. Parker

  * E-mail: rparker@pitt.edu

  Affiliations Department of Chemical and Petroleum Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, United States of America, McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratories, University of Pittsburgh, Pittsburgh, PA, United States of America, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, United States of America

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