Presence of Neutrophil Extracellular Traps and Citrullinated Histone H3 in the Bloodstream of Critically Ill Patients

Tomoya Hirose; Shigeto Hamaguchi; Naoya Matsumoto; Taro Irisawa; Masafumi Seki; Osamu Tasaki; Hideo Hosotsubo; Norihisa Yamamoto; Kouji Yamamoto; Yukihiro Akeda; Kazunori Oishi; Kazunori Tomono; Takeshi Shimazu

doi:10.1371/journal.pone.0111755

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Open Access

Peer-reviewed

Research Article

Presence of Neutrophil Extracellular Traps and Citrullinated Histone H3 in the Bloodstream of Critically Ill Patients

Tomoya Hirose ,

* E-mail: htomoya1979@hp-emerg.med.osaka-u.ac.jp

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Shigeto Hamaguchi ,

Contributed equally to this work with: Shigeto Hamaguchi

Affiliation Division of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Naoya Matsumoto,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Taro Irisawa,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Masafumi Seki,

Affiliation Division of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Osamu Tasaki,

Affiliation Department of Emergency Medicine, Unit of Clinical Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Hideo Hosotsubo,

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Norihisa Yamamoto,

Affiliation Division of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Kouji Yamamoto,

Affiliation Department of Medical Innovation, Osaka University Hospital, Osaka, Japan
⨯
Yukihiro Akeda,

Affiliation International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
⨯
Kazunori Oishi,

Affiliation International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
⨯
Kazunori Tomono,

Affiliation Division of Infection Control and Prevention, Osaka University Graduate School of Medicine, Osaka, Japan
⨯
Takeshi Shimazu

Affiliation Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
⨯

Presence of Neutrophil Extracellular Traps and Citrullinated Histone H3 in the Bloodstream of Critically Ill Patients

Tomoya Hirose,
Shigeto Hamaguchi,
Naoya Matsumoto,
Taro Irisawa,
Masafumi Seki,
Osamu Tasaki,
Hideo Hosotsubo,
Norihisa Yamamoto,
Kouji Yamamoto,
Yukihiro Akeda

Published: November 13, 2014
https://doi.org/10.1371/journal.pone.0111755

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