Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons

Open Access

Peer-reviewed

Research Article

Carmelo Sgobio,

Affiliation Transgenics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
David A. Kupferschmidt,

Affiliation Laboratory of Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Guohong Cui,

Affiliation Laboratory of Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland, United States of America
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Lixin Sun,

Affiliation Transgenics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
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Zheng Li,

Affiliation Unit on Synapse Development and Plasticity, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States of America
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Huaibin Cai ,

* E-mail: caih@mail.nih.gov (HC); lovindav@mail.nih.gov (DML)

Affiliation Transgenics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
David M. Lovinger

* E-mail: caih@mail.nih.gov (HC); lovindav@mail.nih.gov (DML)

Affiliation Laboratory of Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland, United States of America
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Mouse models
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Genetically modified animals
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Neurons
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Neostriatum
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Axons
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Functional electrical stimulation
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Dopamine
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Dopaminergics
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