Topical Application of a Platelet Activating Factor Receptor Agonist Suppresses Phorbol Ester-Induced Acute and Chronic Inflammation and Has Cancer Chemopreventive Activity in Mouse Skin

Ravi P. Sahu; Samin Rezania; Jesus A. Ocana; Sonia C. DaSilva-Arnold; Joshua R. Bradish; Justin D. Richey; Simon J. Warren; Badri Rashid; Jeffrey B. Travers; Raymond L. Konger

doi:10.1371/journal.pone.0111608

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Research Article

Topical Application of a Platelet Activating Factor Receptor Agonist Suppresses Phorbol Ester-Induced Acute and Chronic Inflammation and Has Cancer Chemopreventive Activity in Mouse Skin

Ravi P. Sahu ,

Contributed equally to this work with: Ravi P. Sahu, Samin Rezania

Affiliation Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Samin Rezania ,

Contributed equally to this work with: Ravi P. Sahu, Samin Rezania

Affiliation Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Jesus A. Ocana,

Affiliation Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Sonia C. DaSilva-Arnold,

Affiliations Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America, Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Joshua R. Bradish,

Affiliation Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Justin D. Richey,

Affiliation Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Simon J. Warren,

Affiliation Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Badri Rashid,

Affiliation Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯
Jeffrey B. Travers,

Affiliations Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America, Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, IN, 46202, United States of America
⨯
Raymond L. Konger

* E-mail: rkonger@iupui.edu

Affiliations Departments of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America, Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, 46202, United States of America
⨯

Topical Application of a Platelet Activating Factor Receptor Agonist Suppresses Phorbol Ester-Induced Acute and Chronic Inflammation and Has Cancer Chemopreventive Activity in Mouse Skin

Ravi P. Sahu,
Samin Rezania,
Jesus A. Ocana,
Sonia C. DaSilva-Arnold,
Joshua R. Bradish,
Justin D. Richey,
Simon J. Warren,
Badri Rashid,
Jeffrey B. Travers,
Raymond L. Konger

Published: November 6, 2014
https://doi.org/10.1371/journal.pone.0111608

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