Prostate Cancer Characteristics Associated with Response to Pre-Receptor Targeting of the Androgen Axis

Elahe A. Mostaghel; Andrew Morgan; Xiaotun Zhang; Brett T. Marck; Jing Xia; Rachel Hunter-Merrill; Roman Gulati; Stephen Plymate; Robert L. Vessella; Eva Corey; Celestia S. Higano; Alvin M. Matsumoto; R. Bruce Montgomery; Peter S. Nelson

doi:10.1371/journal.pone.0111545

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Open Access

Peer-reviewed

Research Article

Prostate Cancer Characteristics Associated with Response to Pre-Receptor Targeting of the Androgen Axis

Elahe A. Mostaghel ,

* E-mail: emostagh@fhcrc.org

Affiliations Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Andrew Morgan,

Affiliation Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Xiaotun Zhang,

Affiliation Department of Urology, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Brett T. Marck,

Affiliations Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America, Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, United States of America
⨯
Jing Xia,

Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Rachel Hunter-Merrill,

Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Roman Gulati,

Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Stephen Plymate,

Affiliations Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America, Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, United States of America
⨯
Robert L. Vessella,

Affiliation Department of Urology, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Eva Corey,

Affiliation Department of Urology, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Celestia S. Higano,

Affiliation Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Alvin M. Matsumoto,

Affiliations Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America, Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, United States of America
⨯
R. Bruce Montgomery,

Affiliation Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯
Peter S. Nelson

Affiliations Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, United States of America
⨯

Prostate Cancer Characteristics Associated with Response to Pre-Receptor Targeting of the Androgen Axis

Elahe A. Mostaghel,
Andrew Morgan,
Xiaotun Zhang,
Brett T. Marck,
Jing Xia,
Rachel Hunter-Merrill,
Roman Gulati,
Stephen Plymate,
Robert L. Vessella,
Eva Corey

Published: October 30, 2014
https://doi.org/10.1371/journal.pone.0111545

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Prostate cancer
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Castration
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Androgens
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Cancer treatment
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Cancers and neoplasms
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Gene expression
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Steroids
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