A Comparison of Three Electrophysiological Methods for the Assessment of Disease Status in a Mild Spinal Muscular Atrophy Mouse Model

Open Access

Peer-reviewed

Research Article

Jia Li,

Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Tom R. Geisbush,

Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
William D. Arnold,

Affiliation Department of Neurology, Ohio State University, Columbus, Ohio, United States of America
⨯
Glenn D. Rosen,

Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Phillip G. Zaworski,

Affiliation PharmOptima, LLC, Portage, Michigan, United States of America
⨯
Seward B. Rutkove

* E-mail: srutkove@bidmc.harvard.edu

Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

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Muscle electrophysiology
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Motor neurons
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Mouse models
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Muscle analysis
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Electrophysiology
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Body weight
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Spinal cord
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Biomarkers
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