IL22 Regulates Human Urothelial Cell Sensory and Innate Functions through Modulation of the Acetylcholine Response, Immunoregulatory Cytokines and Antimicrobial Peptides: Assessment of an In Vitro Model

Phong T. Le; Meghan M. Pearce; Shubin Zhang; Edward M. Campbell; Cynthia S. Fok; Elizabeth R. Mueller; Cynthia A. Brincat; Alan J. Wolfe; Linda Brubaker

doi:10.1371/journal.pone.0111375

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Peer-reviewed

Research Article

IL22 Regulates Human Urothelial Cell Sensory and Innate Functions through Modulation of the Acetylcholine Response, Immunoregulatory Cytokines and Antimicrobial Peptides: Assessment of an In Vitro Model

Phong T. Le ,

* E-mail: ple@luc.edu

Affiliation Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
⨯
Meghan M. Pearce,

Affiliation Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
⨯
Shubin Zhang,

Affiliation Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
⨯
Edward M. Campbell,

Affiliation Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
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Cynthia S. Fok,

Affiliation University of Minnesota, Department of Urology, Minneapolis, Minnesota, United States of America
⨯
Elizabeth R. Mueller,

Affiliation Department of Obstetrics and Gynecology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
⨯
Cynthia A. Brincat,

Affiliation Department of Obstetrics and Gynecology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
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Alan J. Wolfe,

Affiliation Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
⨯
Linda Brubaker

Affiliation Department of Obstetrics and Gynecology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, United States of America
⨯

IL22 Regulates Human Urothelial Cell Sensory and Innate Functions through Modulation of the Acetylcholine Response, Immunoregulatory Cytokines and Antimicrobial Peptides: Assessment of an In Vitro Model

Phong T. Le,
Meghan M. Pearce,
Shubin Zhang,
Edward M. Campbell,
Cynthia S. Fok,
Elizabeth R. Mueller,
Cynthia A. Brincat,
Alan J. Wolfe,
Linda Brubaker

Published: October 29, 2014
https://doi.org/10.1371/journal.pone.0111375

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Bladder
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Urothelium
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