Identification of a Novel Drug Lead That Inhibits HCV Infection and Cell-to-Cell Transmission by Targeting the HCV E2 Glycoprotein

• Reem R. Al Olaby,

  Affiliation Department of Chemistry, The American University in Cairo, New Cairo, Egypt

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• Laurence Cocquerel,

  Affiliation Center for Infection and Immunity of Lille, CNRS-UMR8204/Inserm-U1019, Pasteur Institute of Lille, University of Lille North of France, Lille, France

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• Adam Zemla,

  Affiliation Pathogen Bioinformatics, Lawrence Livermore National Laboratory, Livermore, CA, United States of America

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• Laure Saas,

  Affiliation Center for Infection and Immunity of Lille, CNRS-UMR8204/Inserm-U1019, Pasteur Institute of Lille, University of Lille North of France, Lille, France

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• Jean Dubuisson,

  Affiliation Center for Infection and Immunity of Lille, CNRS-UMR8204/Inserm-U1019, Pasteur Institute of Lille, University of Lille North of France, Lille, France

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• Jost Vielmetter,

  Affiliation Protein Expression Center, Beckman Institute, California Institute of Technology, Pasadena, CA, United States of America

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• Joseph Marcotrigiano,

  Affiliation Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, United States of America

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• Abdul Ghafoor Khan,

  Affiliation Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, United States of America

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• Felipe Vences Catalan,

  Affiliation Department of Medicine, Stanford University Medical Center, Stanford, CA, United States of America

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• Alexander L. Perryman,

  Affiliation Department of Medicine, Division of Infectious Diseases, Center for Emerging & Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, NJ, United States of America

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• Joel S. Freundlich,

  Affiliations Department of Medicine, Division of Infectious Diseases, Center for Emerging & Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, NJ, United States of America, Department of Pharmacology and Physiology, Rutgers University-New Jersey Medical School, Newark, NJ, United States of America

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• Stefano Forli,

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America

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• Shoshana Levy,

  Affiliation Department of Medicine, Stanford University Medical Center, Stanford, CA, United States of America

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• Rod Balhorn ,

  * E-mail: rod@shaltech.com

  Current address: SHAL Technologies Inc., Livermore, CA, United States of America

  Affiliation Department of Applied Science, University of California Davis, Davis, CA, United States of America

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• Hassan M. Azzazy

  Affiliation Department of Chemistry, The American University in Cairo, New Cairo, Egypt

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