Expression of the p53 Target Wig-1 Is Associated with HPV Status and Patient Survival in Cervical Carcinoma

Li-Di Xu; Susanne Muller; Srinivasan R. Thoppe; Fredrik Hellborg; Lena Kanter; Mikael Lerner; Biying Zheng; Svetlana Bajalica Lagercrantz; Dan Grandér; Keng Ling Wallin; Klas G. Wiman; Catharina Larsson; Sonia Andersson

doi:10.1371/journal.pone.0111125

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Open Access

Peer-reviewed

Research Article

Expression of the p53 Target Wig-1 Is Associated with HPV Status and Patient Survival in Cervical Carcinoma

Li-Di Xu,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Susanne Muller,

Affiliation Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Srinivasan R. Thoppe,

Affiliation Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Fredrik Hellborg,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Lena Kanter,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Mikael Lerner,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Biying Zheng,

Current address: Department of Clinical Microbiology, Institute of Laboratory Medicine of Guangdong Medical College, Zhanjiang, Guangdong, P.R. China

Affiliation Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Svetlana Bajalica Lagercrantz,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Dan Grandér,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Keng Ling Wallin,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Klas G. Wiman ,

* E-mail: Klas.Wiman@ki.se

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Catharina Larsson,

Affiliation Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska University Hospital-Solna, Stockholm, Sweden
⨯
Sonia Andersson

Affiliation Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska University Hospital-Solna, Stockholm, Sweden
⨯

Expression of the p53 Target Wig-1 Is Associated with HPV Status and Patient Survival in Cervical Carcinoma

Li-Di Xu,
Susanne Muller,
Srinivasan R. Thoppe,
Fredrik Hellborg,
Lena Kanter,
Mikael Lerner,
Biying Zheng,
Svetlana Bajalica Lagercrantz,
Dan Grandér,
Keng Ling Wallin

Published: November 7, 2014
https://doi.org/10.1371/journal.pone.0111125

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Cytoplasmic staining
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Cervical cancer
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Nuclear staining
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Human papillomavirus infection
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