Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation

Patrick Chinestra; Aurélien Olichon; Claire Medale-Giamarchi; Isabelle Lajoie-Mazenc; Rémi Gence; Cyril Inard; Laetitia Ligat; Jean-Charles Faye; Gilles Favre

doi:10.1371/journal.pone.0111034

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Open Access

Peer-reviewed

Research Article

Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation

Patrick Chinestra,

Affiliation Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France
⨯
Aurélien Olichon,

Affiliations Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France, Université Toulouse III-Paul Sabatier, Faculté des Sciences Pharmaceutiques, Toulouse, France
⨯
Claire Medale-Giamarchi,

Affiliations Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France, Université Toulouse III-Paul Sabatier, Faculté des Sciences Pharmaceutiques, Toulouse, France
⨯
Isabelle Lajoie-Mazenc,

Affiliations Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France, Université Toulouse III-Paul Sabatier, Faculté des Sciences Pharmaceutiques, Toulouse, France
⨯
Rémi Gence,

Affiliations Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France, Université Toulouse III-Paul Sabatier, Faculté des Sciences Pharmaceutiques, Toulouse, France
⨯
Cyril Inard,

Affiliation Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France
⨯
Laetitia Ligat,

Affiliation CRCT, plateau de protéomique, Toulouse, France
⨯
Jean-Charles Faye,

Affiliation Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France
⨯
Gilles Favre

* E-mail: favre.gilles@iuct-oncopole.fr

Affiliations Inserm, UMR 1037-CRCT, GTPases Rho dans la progression tumorale, Toulouse, France, Université Toulouse III-Paul Sabatier, Faculté des Sciences Pharmaceutiques, Toulouse, France, Institut Claudius Regaud, Toulouse, France
⨯

Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation

Patrick Chinestra,
Aurélien Olichon,
Claire Medale-Giamarchi,
Isabelle Lajoie-Mazenc,
Rémi Gence,
Cyril Inard,
Laetitia Ligat,
Jean-Charles Faye,
Gilles Favre

Published: November 3, 2014
https://doi.org/10.1371/journal.pone.0111034

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