The Application of Gaussian Mixture Models for Signal Quantification in MALDI-ToF Mass Spectrometry of Peptides

Open Access

Peer-reviewed

Research Article

John Christian G. Spainhour ,

* E-mail: jcs21@musc.edu

Affiliation Medical University of South Carolina, Department of Public Health Sciences, Charleston, South Carolina, United States of America
⨯
Michael G. Janech,

Affiliation Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
John H. Schwacke,

Affiliation Scientific Research Corporation, North Charleston, South Carolina, United States of America
⨯
Juan Carlos Q. Velez,

Affiliations Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina, United States of America
⨯
Viswanathan Ramakrishnan

Affiliation Medical University of South Carolina, Department of Public Health Sciences, Charleston, South Carolina, United States of America
⨯

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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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Signal peptides
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Ionization
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Mass spectra
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Renin-angiotensin system
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Stable isotopes
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Algorithms
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Enzyme-linked immunoassays
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