Fc Gamma Receptor IIb on GM-CSF Macrophages Controls Immune Complex Mediated Inhibition of Inflammatory Signals

Open Access

Peer-reviewed

Research Article

Kim C. M. Santegoets,

Affiliations Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Laboratory of Translational Immunology, Department of Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Rheumatology, Radboud university medical center, Nijmegen, the Netherlands
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Mark H. Wenink,

Affiliations Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Laboratory of Translational Immunology, Department of Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Rheumatology, Radboud university medical center, Nijmegen, the Netherlands
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Wim B. van den Berg,

Affiliation Department of Rheumatology, Radboud university medical center, Nijmegen, the Netherlands
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Timothy R. D. J. Radstake

* E-mail: T.R.D.J.Radstake@umcutrecht.nl

Affiliations Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Laboratory of Translational Immunology, Department of Immunology, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Rheumatology, Radboud university medical center, Nijmegen, the Netherlands
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Macrophages
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Cytokines
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Signal inhibition
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T cells
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Rheumatoid arthritis
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Immune receptor signaling
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Toll-like receptors
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Inflammation
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