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Open Access
Peer-reviewed
Research Article
In Vivo Experiments Reveal the Good, the Bad and the Ugly Faces of sFlt-1 in Pregnancy
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Gabor Szalai ,
Contributed equally to this work with: Gabor Szalai, Yi Xu
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Yi Xu ,
Contributed equally to this work with: Gabor Szalai, Yi Xu
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Roberto Romero ,
* E-mail: romeror@mail.nih.gov (RR); nthan@med.wayne.edu (NGT)
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Tinnakorn Chaiworapongsa,
Affiliations Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, United States of America
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Zhonghui Xu,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Po Jen Chiang,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Hyunyoung Ahn,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Birgitta Sundell,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Olesya Plazyo,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Yang Jiang,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Mary Olive,
Affiliations Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America, Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United States of America
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Bing Wang,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Suzanne M. Jacques,
Affiliation Department of Pathology, Wayne State University School of Medicine, Detroit, MI, United States of America
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Faisal Qureshi,
Affiliation Department of Pathology, Wayne State University School of Medicine, Detroit, MI, United States of America
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Adi L. Tarca,
Affiliations Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America, Department of Computer Science, Wayne State University, Detroit, MI, United States of America, Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, United States of America
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Offer Erez,
Affiliation Department of Obstetrics and Gynecology, Soroka University Medical Center, School of Medicine, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
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Zhong Dong,
Affiliation Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America
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Zoltan Papp,
Affiliation Maternity Private Department, Kutvolgyi Clinical Block, Semmelweis University, Budapest, Hungary
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Sonia S. Hassan,
Affiliations Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, United States of America
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Edgar Hernandez-Andrade,
Affiliations Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, United States of America
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Nandor Gabor Than
* E-mail: romeror@mail.nih.gov (RR); nthan@med.wayne.edu (NGT)
Affiliations Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, United States of America, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, United States of America, Maternity Private Department, Kutvolgyi Clinical Block, Semmelweis University, Budapest, Hungary, Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary
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In Vivo Experiments Reveal the Good, the Bad and the Ugly Faces of sFlt-1 in Pregnancy
- Gabor Szalai,
- Yi Xu,
- Roberto Romero,
- Tinnakorn Chaiworapongsa,
- Zhonghui Xu,
- Po Jen Chiang,
- Hyunyoung Ahn,
- Birgitta Sundell,
- Olesya Plazyo,
- Yang Jiang
- Published: November 13, 2014
- https://doi.org/10.1371/journal.pone.0110867