ASP4058, a Novel Agonist for Sphingosine 1-Phosphate Receptors 1 and 5, Ameliorates Rodent Experimental Autoimmune Encephalomyelitis with a Favorable Safety Profile

• Rie Yamamoto,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Youhei Okada,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Jun Hirose,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Tadatsura Koshika,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Yuka Kawato,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Masashi Maeda,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Rika Saito,

  Affiliation Kashima R&D Center, Drug Discovery Research, Astellas Pharma Inc., Osaka, Japan

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• Kazuyuki Hattori,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Hironori Harada,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Yasuhisa Nagasaka,

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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• Tatsuaki Morokata

  * E-mail: tatsuaki.morokata@astellas.com

  Affiliation Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc., Ibaraki, Japan

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