CD4+ and CD8+ T Cell Activation Are Associated with HIV DNA in Resting CD4+ T Cells

Leslie R. Cockerham; Janet D. Siliciano; Elizabeth Sinclair; Una O'Doherty; Sarah Palmer; Steven A. Yukl; Matt C. Strain; Nicolas Chomont; Frederick M. Hecht; Robert F. Siliciano; Douglas D. Richman; Steven G. Deeks

doi:10.1371/journal.pone.0110731

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Open Access

Peer-reviewed

Research Article

CD4⁺ and CD8⁺ T Cell Activation Are Associated with HIV DNA in Resting CD4⁺ T Cells

Leslie R. Cockerham ,

* E-mail: leslie.cockerham@ucsf.edu

Affiliation HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
⨯
Janet D. Siliciano,

Affiliation Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Elizabeth Sinclair,

Affiliation Division of Experimental Medicine, University of California San Francisco, San Francisco, California, United States of America
⨯
Una O'Doherty,

Affiliation University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Sarah Palmer,

Affiliations Westmead Millennium Institute for Medical Research, Westmead, Australia, University of Sydney, Sydney, Australia, Karolinska Institutet, Stockholm, Sweden
⨯
Steven A. Yukl,

Affiliation San Francisco VA Medical Center, San Francisco, California, United States of America
⨯
Matt C. Strain,

Affiliation Veterans Affairs San Diego Healthcare System, San Diego, California, United States of America
⨯
Nicolas Chomont,

Affiliation Vaccine and Gene Therapy Institute Florida, Port St. Lucie, Florida, United States of America
⨯
Frederick M. Hecht,

Affiliation HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
⨯
Robert F. Siliciano,

Affiliations Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Howard Hughes Medical Institute, Baltimore, Maryland, United States of America
⨯
Douglas D. Richman,

Affiliations Veterans Affairs San Diego Healthcare System, San Diego, California, United States of America, University of California San Diego, La Jolla, California, United States of America
⨯
Steven G. Deeks

Affiliation HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
⨯

CD4⁺ and CD8⁺ T Cell Activation Are Associated with HIV DNA in Resting CD4⁺ T Cells

Leslie R. Cockerham,
Janet D. Siliciano,
Elizabeth Sinclair,
Una O'Doherty,
Sarah Palmer,
Steven A. Yukl,
Matt C. Strain,
Nicolas Chomont,
Frederick M. Hecht,
Robert F. Siliciano

Published: October 23, 2014
https://doi.org/10.1371/journal.pone.0110731

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