β₂-Adrenergic Receptor-Dependent Attenuation of Hypoxic Pulmonary Vasoconstriction Prevents Progression of Pulmonary Arterial Hypertension in Intermittent Hypoxic Rats

• Hisashi Nagai ,

  * E-mail: nagai@legalmed.jp

  Affiliations Department of Forensic Medicine, Tokyo Medical and Dental University, Tokyo, Japan, Department of Forensic Medicine, The University of Tokyo, Tokyo, Japan, Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan

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• Ichiro Kuwahira,

  Affiliation Department of Pulmonary Medicine, Tokai University Tokyo Hospital, Tokyo, Japan

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• Daryl O. Schwenke,

  Affiliation Department of Physiology-Heart Otago, University of Otago, Dunedin, New Zealand

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• Hirotsugu Tsuchimochi,

  Affiliation Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan

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• Akina Nara,

  Affiliation Department of Forensic Medicine, The University of Tokyo, Tokyo, Japan

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• Tadakatsu Inagaki,

  Affiliation Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan

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• Sayoko Ogura,

  Affiliations Department of Forensic Medicine, The University of Tokyo, Tokyo, Japan, Division of Laboratory Medicine, Department of Pathology and Microbiology, Faculty of Medicine, Nihon University School of Medicine, Tokyo, Japan

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• Yutaka Fujii,

  Affiliation Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan

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• Keiji Umetani,

  Affiliation Japan Synchrotron Radiation Research Institute, Hyogo, Japan

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• Tatsuo Shimosawa,

  Affiliation Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan

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• Ken-ichi Yoshida,

  Affiliations Department of Forensic Medicine, The University of Tokyo, Tokyo, Japan, Department of Forensic Medicine, Tokyo Medical University, Tokyo, Japan

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• James T. Pearson,

  Affiliations Monash Biomedical Imaging Facility and Department of Physiology, Monash University, Melbourne, Clayton, Victoria, Australia, Australian Synchrotron, Clayton, Victoria, Australia

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• Koichi Uemura,

  Affiliation Department of Forensic Medicine, Tokyo Medical and Dental University, Tokyo, Japan

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• Mikiyasu Shirai

  Affiliation Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan

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