Divergent Gene Activation in Peripheral Blood and Tissues of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis following Infliximab Therapy

Alexander Rosenberg; Hongtao Fan; Yahui G. Chiu; Rebecca Bolce; Darren Tabechian; Rick Barrett; Sharon Moorehead; Frédéric Baribaud; Hao Liu; Nancy Peffer; David Shealy; Edward M. Schwarz; Christopher T. Ritchlin

doi:10.1371/journal.pone.0110657

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Open Access

Peer-reviewed

Research Article

Divergent Gene Activation in Peripheral Blood and Tissues of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis following Infliximab Therapy

Alexander Rosenberg,

Affiliation Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Hongtao Fan,

Affiliation Janssen Research and Development LLC, Spring House, PA, United States of America
⨯
Yahui G. Chiu,

Affiliation Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Rebecca Bolce,

Affiliation Janssen Research and Development LLC, Spring House, PA, United States of America
⨯
Darren Tabechian,

Affiliation Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Rick Barrett,

Affiliation Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Sharon Moorehead,

Affiliation Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Frédéric Baribaud,

Affiliation Janssen Research and Development LLC, Spring House, PA, United States of America
⨯
Hao Liu,

Affiliation Janssen Research and Development LLC, Spring House, PA, United States of America
⨯
Nancy Peffer,

Affiliation Janssen Research and Development LLC, Spring House, PA, United States of America
⨯
David Shealy,

Affiliation Janssen Research and Development LLC, Spring House, PA, United States of America
⨯
Edward M. Schwarz,

Affiliation The Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Christopher T. Ritchlin

* E-mail: Christopher_Ritchlin@urmc.rochester.edu

Affiliations Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States of America, The Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America
⨯

Divergent Gene Activation in Peripheral Blood and Tissues of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis following Infliximab Therapy

Alexander Rosenberg,
Hongtao Fan,
Yahui G. Chiu,
Rebecca Bolce,
Darren Tabechian,
Rick Barrett,
Sharon Moorehead,
Frédéric Baribaud,
Hao Liu,
Nancy Peffer

Published: October 21, 2014
https://doi.org/10.1371/journal.pone.0110657

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Gene expression
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Biopsy
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Psoriatic arthritis
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Microarrays
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Regulator genes
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Blood
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Rheumatoid arthritis
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