Cutaneous Epithelial Tumors Induced by Vemurafenib Involve the MAPK and Pi3KCA Pathways but Not HPV nor HPyV Viral Infection

Eric Frouin; Bernard Guillot; Marion Larrieux; Ariane Tempier; Nathalie Boulle; Vincent Foulongne; Céline Girard; Valérie Costes; Jérome Solassol

doi:10.1371/journal.pone.0110478

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Peer-reviewed

Research Article

Cutaneous Epithelial Tumors Induced by Vemurafenib Involve the MAPK and Pi3KCA Pathways but Not HPV nor HPyV Viral Infection

Eric Frouin ,

* E-mail: efrouin@orange.fr

Affiliations Department of Biopathology, CHU Montpellier, Montpellier, France, University of Montpellier I, Montpellier, France
⨯
Bernard Guillot,

Affiliations University of Montpellier I, Montpellier, France, Department of Dermatology, CHU Montpellier, Montpellier, France, U1058, INSERM, University of Montpellier I, Montpellier, France
⨯
Marion Larrieux,

Affiliation Department of Biopathology, CHU Montpellier, Montpellier, France
⨯
Ariane Tempier,

Affiliation Department of Biopathology, CHU Montpellier, Montpellier, France
⨯
Nathalie Boulle,

Affiliations Department of Biopathology, CHU Montpellier, Montpellier, France, University of Montpellier I, Montpellier, France
⨯
Vincent Foulongne,

Affiliations University of Montpellier I, Montpellier, France, U1058, INSERM, University of Montpellier I, Montpellier, France, Department of Virology, CHU Montpellier, Montpellier, France
⨯
Céline Girard,

Affiliations University of Montpellier I, Montpellier, France, Department of Dermatology, CHU Montpellier, Montpellier, France, U1058, INSERM, University of Montpellier I, Montpellier, France
⨯
Valérie Costes,

Affiliations Department of Biopathology, CHU Montpellier, Montpellier, France, University of Montpellier I, Montpellier, France, U1058, INSERM, University of Montpellier I, Montpellier, France
⨯
Jérome Solassol

Affiliations Department of Biopathology, CHU Montpellier, Montpellier, France, University of Montpellier I, Montpellier, France, Department of Clinical Oncoproteomics, Montpellier Cancer Institute (ICM), Montpellier, France
⨯

Cutaneous Epithelial Tumors Induced by Vemurafenib Involve the MAPK and Pi3KCA Pathways but Not HPV nor HPyV Viral Infection

Eric Frouin,
Bernard Guillot,
Marion Larrieux,
Ariane Tempier,
Nathalie Boulle,
Vincent Foulongne,
Céline Girard,
Valérie Costes,
Jérome Solassol

Published: October 31, 2014
https://doi.org/10.1371/journal.pone.0110478

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