Browning of White Adipose Tissue Uncouples Glucose Uptake from Insulin Signaling

Karin Mössenböck; Alexandros Vegiopoulos; Adam J. Rose; Tjeerd P. Sijmonsma; Stephan Herzig; Tobias Schafmeier

doi:10.1371/journal.pone.0110428

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Peer-reviewed

Research Article

Browning of White Adipose Tissue Uncouples Glucose Uptake from Insulin Signaling

Karin Mössenböck,

Affiliation Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, Heidelberg, Germany
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Alexandros Vegiopoulos,

Affiliations Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, Heidelberg, Germany, Junior research group Metabolism and Stem Cell Plasticity, German Cancer Research Center (DKFZ), Heidelberg, Germany
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Adam J. Rose,

Affiliation Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, Heidelberg, Germany
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Tjeerd P. Sijmonsma,

Affiliation Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, Heidelberg, Germany
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Stephan Herzig ,

* E-mail: s.herzig@dkfz.de

Affiliation Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, Heidelberg, Germany
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Tobias Schafmeier

Affiliation Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, Heidelberg, Germany
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Browning of White Adipose Tissue Uncouples Glucose Uptake from Insulin Signaling

Karin Mössenböck,
Alexandros Vegiopoulos,
Adam J. Rose,
Tjeerd P. Sijmonsma,
Stephan Herzig,
Tobias Schafmeier

Published: October 14, 2014
https://doi.org/10.1371/journal.pone.0110428

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Insulin
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Adipocytes
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Brown adipose tissue
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Glucose
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Adipose tissue
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Adipocyte differentiation
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Gene expression
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